Plant Transcription Factor Database
Previous version: v3.0
Camelina sativa
SBP Family
Species TF ID Description
Csa00566s020.1SBP family protein
Csa01g017810.1SBP family protein
Csa02g039260.1SBP family protein
Csa03g001150.1SBP family protein
Csa03g024850.1SBP family protein
Csa03g030570.1SBP family protein
Csa03g030580.1SBP family protein
Csa03g060290.1SBP family protein
Csa04g044410.1SBP family protein
Csa04g057680.1SBP family protein
Csa04g066210.1SBP family protein
Csa04g066220.1SBP family protein
Csa05g002060.1SBP family protein
Csa05g002060.2SBP family protein
Csa05g009390.1SBP family protein
Csa05g021470.1SBP family protein
Csa05g085850.1SBP family protein
Csa05g091650.1SBP family protein
Csa06g033730.1SBP family protein
Csa06g048230.1SBP family protein
Csa06g053600.1SBP family protein
Csa07g005050.1SBP family protein
Csa07g007510.1SBP family protein
Csa07g035820.1SBP family protein
Csa07g048160.1SBP family protein
Csa08g011360.1SBP family protein
Csa09g070470.1SBP family protein
Csa09g081320.1SBP family protein
Csa11g071660.1SBP family protein
Csa11g082000.1SBP family protein
Csa13g021690.1SBP family protein
Csa13g021690.2SBP family protein
Csa13g030290.1SBP family protein
Csa14g026180.1SBP family protein
Csa14g034910.1SBP family protein
Csa14g034920.1SBP family protein
Csa14g063510.1SBP family protein
Csa15g019750.1SBP family protein
Csa16g005930.1SBP family protein
Csa16g007310.1SBP family protein
Csa16g030470.1SBP family protein
Csa16g040730.1SBP family protein
Csa17090s010.1SBP family protein
Csa17g002540.1SBP family protein
Csa17g026870.1SBP family protein
Csa17g036060.1SBP family protein
Csa17g036070.1SBP family protein
Csa17g093410.1SBP family protein
Csa18g010590.1SBP family protein
Csa18g021350.1SBP family protein
Csa19g021980.1SBP family protein
Csa20g027300.1SBP family protein
Csa20g067170.1SBP family protein
Csa20g067170.2SBP family protein
SBP Family Introduction

SQUAMOSA promoter binding proteins (SBPs) form a major family of plant-specific transcription factors related to flower development. Although SBPs are heterogeneous in primary structure, they share a highly conserved DNA-binding domain (DBD) that has been suggested to be zinc binding. Here we report the NMR solution structures of DBDs of two SBPs of Arabidopsis thaliana, SPL4 and SPL7. The two share essentially the same structural features. Each structure contains two zinc-binding sites consisting of eight Cys or His residues in a Cys3HisCys2HisCys or Cys6HisCys sequence motif in which the first four residues coordinate to one zinc and the last four coordinate to the other. These structures are dissimilar to other known zinc-binding structures, and thus represent a novel type of zinc-binding motif. The electrostatic profile on the surface suggested that a continuous region, including all the conserved basic residues, is involved in the DNA binding, the mode of which is likely to be novel as well.

Yamasaki K, Kigawa T, Inoue M, Tateno M, Yamasaki T, Yabuki T, Aoki M, Seki E, Matsuda T, Nunokawa E, Ishizuka Y, Terada T, Shirouzu M, Osanai T, Tanaka A, Seki M, Shinozaki K, Yokoyama S.
A novel zinc-binding motif revealed by solution structures of DNA-binding domains of Arabidopsis SBP-family transcription factors
J Mol Biol. 2004 Mar 12;337(1):49-63.
PMID: 15001351

SBP-box genes were first characterized as SQUAMOSA promoter binding proteins (SBPs) to regulate the expression of MADS-box genes in early flower development of A. majus (Klein et al., 1996). Since then, SBP-box genes have been identified in many plants including green alga, moss, silver birch, A. majus, Arabidopsis and maize. They play critical roles in regulating flower and fruit development as well as other physiological processes ([Moreno et al., 1997],[Eriksson et al., 2004], [Lannenpaa et al., 2004], [Arazi et al., 2005] and [Kropat et al., 2005]). It has been reported that Arabidopsis SPL3, SPL8 and SPL14 involves in flowering, sporogenesis, GA signaling and toxin resistance ([Cardon et al., 1997], [Unte et al., 2003], [Stone et al., 2005] and [Zhang et al., 2006]) while maize tga1 and tomato LeSPL-CNR affect fruit development ([Wang et al., 2005a] and [Manning et al., 2006]).

SBP-box genes encode proteins sharing a conserved DNA-binding domain of 79 amino acid residues. It has been proved that the DNA-binding domain of SBP-box genes is necessary and sufficient to bind to a palindromic GTAC core motif ([Klein et al., 1996], [Cardon et al., 1997], [Cardon et al., 1999], [Lannenpaa et al., 2004] and [Birkenbihl et al., 2005]). Studies on the NMR solution structure of the fragment of Arabidopsis SPL4 and SPL7 revealed that the DNA-binding domain of SBPs consisted of two separate zinc-binding sites. One zinc finger is C3H or C4 and the other is C2HC (Yamasaki et al., 2004 K. Yamasaki et al.,).

Guo AY, Zhu QH, Gu X, Ge S, Yang J, Luo J.
Genome-wide identification and evolutionary analysis of the plant specific SBP-box transcription factor family.
Gene. 2008 Jul 15;418(1-2):1-8.
PMID: 18495384